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Vigilance der Tierarzneimittel: Gemeldete unerwünschte Wirkungen im Jahr 2007


Müntener, C R; Bruckner, L; Stürer, A; Althaus, F R; Schneider, A (2009). Vigilance der Tierarzneimittel: Gemeldete unerwünschte Wirkungen im Jahr 2007. Schweizer Archiv für Tierheilkunde, 151(1):12-20.

Abstract

163 reports of suspected adverse reactions were received in the year 2007: 111 for veterinary medicinal (VMPs) and 52 for immunologic products. Half of the reported reactions for VMPs concerned either an antiparasitic drug (26%) or an antibiotic (24%). Reconversions (use in another target species or for another indication as registered) made the third most frequently mentioned group with 11 reports. For immunologicals, half of the declarations were related to an adverse reaction in dogs, the most frequently reported reaction in companion animals being allergies. Moreover, 272 enquiries were received by the Swiss Toxicological Information Center in Zürich. Most of these were related to dogs (73%) and the number of enquiries regarding VMPs correlated positively with the most frequently used therapeutic classes like antiparasitics (47%) and anti-inflammatory drugs (23%). The complexity of proscessing reports regarding the detection of residues in milk after prescribed withdrawal times is discussed in detail. In conclusion, the year 2007 is seen as a consolidation of the established system with a tendency towards increase in the number of complex cases.

Abstract

163 reports of suspected adverse reactions were received in the year 2007: 111 for veterinary medicinal (VMPs) and 52 for immunologic products. Half of the reported reactions for VMPs concerned either an antiparasitic drug (26%) or an antibiotic (24%). Reconversions (use in another target species or for another indication as registered) made the third most frequently mentioned group with 11 reports. For immunologicals, half of the declarations were related to an adverse reaction in dogs, the most frequently reported reaction in companion animals being allergies. Moreover, 272 enquiries were received by the Swiss Toxicological Information Center in Zürich. Most of these were related to dogs (73%) and the number of enquiries regarding VMPs correlated positively with the most frequently used therapeutic classes like antiparasitics (47%) and anti-inflammatory drugs (23%). The complexity of proscessing reports regarding the detection of residues in milk after prescribed withdrawal times is discussed in detail. In conclusion, the year 2007 is seen as a consolidation of the established system with a tendency towards increase in the number of complex cases.

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Additional indexing

Other titles:Vigilance for veterinary medicinal products: Declarations of suspected adverse reactions in the year 2007
Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Pharmacology and Toxicology
Dewey Decimal Classification:570 Life sciences; biology
Uncontrolled Keywords:Delvo-Test - Pharmacovigilance - Rückstände - Umwidmung - Vaccinovigilance
Language:German
Date:2009
Deposited On:31 Mar 2009 13:59
Last Modified:06 Dec 2017 19:23
Publisher:Hans Huber
ISSN:0036-7281
Funders:others
Publisher DOI:https://doi.org/10.1024/0036-7281.151.1.12
PubMed ID:19160166

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