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Pharmacotherapy of acute coronary syndromes: medical economics with an emphasis on clopidogrel


Bramkamp, M; Dedes, K J; Szucs, T D (2005). Pharmacotherapy of acute coronary syndromes: medical economics with an emphasis on clopidogrel. Cardiovascular Drugs and Therapy, 19(4):291-299.

Abstract

Acute coronary syndromes account worldwide for a significant burden of hospital- and societal costs. Pharmacotherapy of acute coronary syndromes consists of a combined antithrombotic therapy. Remarkable therapeutic advances have been made with the introduction of glycoprotein IIb/IIIa receptor inhibitors, low molecular weight heparins and thienopyridines, such as clopidogrel. Based on positive clinical data of large randomized trials numerous cost studies have been undertaken to analyse the cost-effectiveness of these new drugs. Most of them are showing an acceptable level of cost-effectiveness for the new treatments. Taking all available cost-studies into account, we conclude that new antithrombotic treatments are cost-effective as long as their use is limited to selected patient populations.

Abstract

Acute coronary syndromes account worldwide for a significant burden of hospital- and societal costs. Pharmacotherapy of acute coronary syndromes consists of a combined antithrombotic therapy. Remarkable therapeutic advances have been made with the introduction of glycoprotein IIb/IIIa receptor inhibitors, low molecular weight heparins and thienopyridines, such as clopidogrel. Based on positive clinical data of large randomized trials numerous cost studies have been undertaken to analyse the cost-effectiveness of these new drugs. Most of them are showing an acceptable level of cost-effectiveness for the new treatments. Taking all available cost-studies into account, we conclude that new antithrombotic treatments are cost-effective as long as their use is limited to selected patient populations.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2005
Deposited On:08 Jun 2009 16:01
Last Modified:05 Apr 2016 13:15
Publisher:Springer
ISSN:0920-3206
Additional Information:SpringerLink – Full text article
Publisher DOI:https://doi.org/10.1007/s10557-005-3694-7
Official URL:http://www.springerlink.com/content/f06k707623t83138/fulltext.pdf
PubMed ID:16187005

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