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Drosophila Myc


Gallant, P (2009). Drosophila Myc. Advances in Cancer Research, 103(1):111-144.

Abstract

Myc genes play a major role in human cancer, and they are important regulators of growth and proliferation during normal development. Despite intense study over the last three decades, many aspects of Myc function remain poorly understood. The identification of a single Myc homolog in the model organism Drosophila melanogaster more than 10 years ago has opened new possibilities for addressing these issues. This review summarizes what the last decade has taught us about Myc biology in the fruit fly.

Abstract

Myc genes play a major role in human cancer, and they are important regulators of growth and proliferation during normal development. Despite intense study over the last three decades, many aspects of Myc function remain poorly understood. The identification of a single Myc homolog in the model organism Drosophila melanogaster more than 10 years ago has opened new possibilities for addressing these issues. This review summarizes what the last decade has taught us about Myc biology in the fruit fly.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Institute of Zoology (former)
Dewey Decimal Classification:570 Life sciences; biology
590 Animals (Zoology)
Uncontrolled Keywords:Drosophila, genetics, cancer, growth, transcription, apoptosis, competition
Date:2009
Deposited On:11 Nov 2009 08:41
Last Modified:05 Apr 2016 13:31
Publisher:Elsevier
ISSN:0065-230X
Publisher DOI:https://doi.org/10.1016/S0065-230X(09)03005-X
PubMed ID:19854354

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