BACKGROUND AND OBJECTIVE: To investigate the effect of early photocoagulation in central serous chorioretinopathy. PATIENTS AND METHODS: In a prospective study, 15 consecutive patients with central serous chorioretinopathy and single leakage points were treated with photocoagulation between 2 days and 8 weeks after onset of symptoms. The main outcome measures were best-corrected visual acuity and metamorphopsias (Amsler grid) at months 1 and 4 compared with baseline. RESULTS: Mean visual acuity improved by 1.53 lines 1 month after treatment. The mean squares involved in the Amsler grid were reduced by 2.07 squares. No relapse occurred during the follow-up period. CONCLUSION: Considering the characteristics of individuals affected by central serous chorioretinopathy, a fast recovery would be advantageous. This study identified early laser photocoagulation in central serous chorioretinopathy as an effective treatment regarding resorption of subretinal fluid, recovery of visual acuity, and improvement of metamorphopsia. Copyright 2009, SLACK Incorporated.