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Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes


Membrino, A; Paramasivam, M; Cogoi, S; Alzeer, J; Luedtke, N W; Xodo, L E (2010). Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes. Chemical Communications, 46(4):625-627.

Abstract

Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.

Abstract

Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Language:English
Date:2010
Deposited On:24 Jan 2010 10:14
Last Modified:21 Nov 2017 14:33
Publisher:Royal Society of Chemistry
ISSN:1359-7345
Additional Information:Publikationsdatum der Epub-Version: 2009 Nov 20
Publisher DOI:https://doi.org/10.1039/b918964e
PubMed ID:20062883

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