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Altersbezogene Makuladegeneration (AMD)


Michels, S; Kurz-Levin, M (2009). Altersbezogene Makuladegeneration (AMD). Therapeutische Umschau, 66(3):189-195.

Abstract

Today age-related macular degeneration (AMD) is the most frequent cause for legal blindness in western industrialized countries. The prevalence of this disease rises with increasing age. A multifactorial pathogenesis of AMD is postulated including genetic predisposition and environmental risk factors. The most relevant modifiable risk factor is smoking. Up to today there is no cure of this chronic disease. Prophylaxis, including a healthy diet and antioxidants as nutrional supplements for selected patients, aims to slow down the disease progression. Significant progress has been made in the treatment of the neovascular form of the disease using inhibitors of the vascular endothelial growth factor (VEGF).

Abstract

Today age-related macular degeneration (AMD) is the most frequent cause for legal blindness in western industrialized countries. The prevalence of this disease rises with increasing age. A multifactorial pathogenesis of AMD is postulated including genetic predisposition and environmental risk factors. The most relevant modifiable risk factor is smoking. Up to today there is no cure of this chronic disease. Prophylaxis, including a healthy diet and antioxidants as nutrional supplements for selected patients, aims to slow down the disease progression. Significant progress has been made in the treatment of the neovascular form of the disease using inhibitors of the vascular endothelial growth factor (VEGF).

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Additional indexing

Other titles:Age-related macular degeneration (AMD)
Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Ophthalmology Clinic
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2009
Deposited On:03 Jan 2010 12:41
Last Modified:05 Apr 2016 13:42
Publisher:Hans Huber
ISSN:0040-5930
Publisher DOI:https://doi.org/10.1024/0040-5930.66.3.189
PubMed ID:19266466

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