Header

UZH-Logo

Maintenance Infos

Unprecedented selectivity via electronic substrate recognition in the 1,4-addition to cyclic olefins using a chiral disulfoxide Rhodium catalyst


Bürgi, J J; Mariz, R; Gatti, M; Drinkel, E; Luan, X; Blumentritt, S; Linden, A; Dorta, R (2009). Unprecedented selectivity via electronic substrate recognition in the 1,4-addition to cyclic olefins using a chiral disulfoxide Rhodium catalyst. Angewandte Chemie Internationale Edition, 48(15):2768-2771.

Abstract

From zero to hero? Sulfoxides are generally not considered useful ligand entities in asymmetric metal catalysis. However, a chiral disulfoxide as a chelating ligand in the rhodium-catalyzed 1,4-addition of aryl boronic acids to cyclic, ,-unsaturated ketones and esters gives impressive catalytic results, thus opening the door to future applications of this new chiral ligand class.

Abstract

From zero to hero? Sulfoxides are generally not considered useful ligand entities in asymmetric metal catalysis. However, a chiral disulfoxide as a chelating ligand in the rhodium-catalyzed 1,4-addition of aryl boronic acids to cyclic, ,-unsaturated ketones and esters gives impressive catalytic results, thus opening the door to future applications of this new chiral ligand class.

Statistics

Citations

66 citations in Web of Science®
71 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

1 download since deposited on 18 Feb 2010
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Chemistry
Dewey Decimal Classification:540 Chemistry
Language:English
Date:2009
Deposited On:18 Feb 2010 18:16
Last Modified:16 Dec 2016 11:37
Publisher:Wiley-VCH Verlag
ISSN:1433-7851
Funders:Alfred Werner Foundation, SNF, Roche Research Foundation
Publisher DOI:https://doi.org/10.1002/anie.200900429

Download

Preview Icon on Download
Filetype: PDF - Registered users only
Size: 1MB
View at publisher