Header

UZH-Logo

Maintenance Infos

Evaluation of a novel haematology analyser for use with feline blood


Weissenbacher, S; Riond, B; Hofmann-Lehmann, R; Lutz, H (2011). Evaluation of a novel haematology analyser for use with feline blood. Veterinary Journal, 187(3):381-387.

Abstract

A novel haematology analyser was evaluated for its use with feline samples. Complete blood cell counts, a five-part differential count, and reticulocyte numbers were determined, and the results compared with reference data. Coefficients of correlation, Passing-Bablok regression analysis and Bland-Altmann difference plots with biases and 95% limits of agreement are reported. Precision and linearity were also studied. The instrument demonstrated very low imprecision, and the tested range of linearity exceeded the reference ranges provided by the manufacturer. For all parameters except monocytes (r=0.65), the analyser results correlated well with reference methods. Compared with the manual count of aggregated reticulocytes, the instrument showed good agreement with a positive bias. The optical platelet count correlated well with the manual chamber count. In conclusion the analyser was found to be highly reliable for the analysis of feline blood samples in a large veterinary laboratory.

Abstract

A novel haematology analyser was evaluated for its use with feline samples. Complete blood cell counts, a five-part differential count, and reticulocyte numbers were determined, and the results compared with reference data. Coefficients of correlation, Passing-Bablok regression analysis and Bland-Altmann difference plots with biases and 95% limits of agreement are reported. Precision and linearity were also studied. The instrument demonstrated very low imprecision, and the tested range of linearity exceeded the reference ranges provided by the manufacturer. For all parameters except monocytes (r=0.65), the analyser results correlated well with reference methods. Compared with the manual count of aggregated reticulocytes, the instrument showed good agreement with a positive bias. The optical platelet count correlated well with the manual chamber count. In conclusion the analyser was found to be highly reliable for the analysis of feline blood samples in a large veterinary laboratory.

Statistics

Citations

Dimensions.ai Metrics
29 citations in Web of Science®
30 citations in Scopus®
32 citations in Microsoft Academic
Google Scholar™

Altmetrics

Downloads

343 downloads since deposited on 24 Mar 2010
17 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Veterinary Clinic > Department of Farm Animals
Dewey Decimal Classification:570 Life sciences; biology
630 Agriculture
Language:English
Date:2011
Deposited On:24 Mar 2010 14:11
Last Modified:17 Feb 2018 13:04
Publisher:Elsevier
ISSN:1090-0233
OA Status:Green
Publisher DOI:https://doi.org/10.1016/j.tvjl.2010.01.005
PubMed ID:20133174

Download

Download PDF  'Evaluation of a novel haematology analyser for use with feline blood'.
Preview
Content: Accepted Version
Filetype: PDF
Size: 1MB
View at publisher