Header

UZH-Logo

Maintenance Infos

Changing delayed-type sensitizations to the baseline series allergens over a decade at the Zurich University Hospital


Janach, M; Kühne, A; Seifert, Burkhardt; French, L E; Ballmer-Weber, B; Hofbauer, G F L (2010). Changing delayed-type sensitizations to the baseline series allergens over a decade at the Zurich University Hospital. Contact Dermatitis, 63(1):42-78.

Abstract

BACKGROUND: Patch testing detects delayed-type sensitizations and may show changes in prevalence over time. OBJECTIVES: To compare sensitization prevalence to our baseline series allergens during the years 2000-2004 to results from 1990 to 1994. METHODS: We analysed baseline patch test series allergens from 2000 through 2004. RESULTS: 4094 individuals were patch tested to the baseline series (mean age 45.4 years, males 41.7%). The highest sensitization rates were found for nickel sulfate (19.3%), fragrance mix (10.4%) and Myroxylon pereirae (7.8%). Compared to 1990-1994, methylchloroisothiazolinone (and) methylisothiazoline (MCI/MI) and neomycin sulfate sensitization decreased and lanolin alcohol, thiuram mix and ammoniated mercury sensitization increased. CONCLUSIONS: Current sensitization rates are similar to those across Europe. Reduced sensitizations to MCI/MI and neomycin sulfate and increased sensitizations to thiuram mix and ammoniated mercury chloride may well be because of changes in exposure. The current group comprises a higher proportion affected by leg dermatitis and may thus explain the higher sensitization to lanolin alcohol. Comparing patch results over time shows important changes in sensitization prevalence.

Abstract

BACKGROUND: Patch testing detects delayed-type sensitizations and may show changes in prevalence over time. OBJECTIVES: To compare sensitization prevalence to our baseline series allergens during the years 2000-2004 to results from 1990 to 1994. METHODS: We analysed baseline patch test series allergens from 2000 through 2004. RESULTS: 4094 individuals were patch tested to the baseline series (mean age 45.4 years, males 41.7%). The highest sensitization rates were found for nickel sulfate (19.3%), fragrance mix (10.4%) and Myroxylon pereirae (7.8%). Compared to 1990-1994, methylchloroisothiazolinone (and) methylisothiazoline (MCI/MI) and neomycin sulfate sensitization decreased and lanolin alcohol, thiuram mix and ammoniated mercury sensitization increased. CONCLUSIONS: Current sensitization rates are similar to those across Europe. Reduced sensitizations to MCI/MI and neomycin sulfate and increased sensitizations to thiuram mix and ammoniated mercury chloride may well be because of changes in exposure. The current group comprises a higher proportion affected by leg dermatitis and may thus explain the higher sensitization to lanolin alcohol. Comparing patch results over time shows important changes in sensitization prevalence.

Statistics

Citations

Dimensions.ai Metrics
1 citation in Web of Science®
2 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

2 downloads since deposited on 15 Jul 2010
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:June 2010
Deposited On:15 Jul 2010 08:49
Last Modified:20 Feb 2018 01:33
Publisher:Wiley-Blackwell
ISSN:0105-1873
OA Status:Closed
Publisher DOI:https://doi.org/10.1111/j.1600-0536.2010.01727.x
PubMed ID:20597933

Download