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Intraurethral Imiquimod for Extensive Urethral Genital Warts (Condylomata Acuminata)


Tremp, M; Hafner, J; Sulser, T; Müntener, M (2010). Intraurethral Imiquimod for Extensive Urethral Genital Warts (Condylomata Acuminata). BJU International:online.

Abstract

We present the case of a 55 year old patient under immunosuppressive treatment who developed multiple anogenital condylomata acuminata. Urethroscopy showed extensive condylomatous involvement of the entire penile urethra. Due to the potential morbidity of any surgical approach, we opted for an experimental treatment with Imiquimod (250 mg 5%-Imiquimod intraurethrally 3 times weekly), which was well tolerated. After a remarkable initial response and a continuous decline in the number of lesions, only minimal residual condylomata were left after 15 months. These were resected with the Holmium:YAG laser. Follow-up urethroscopy at three months showed no recurrence or signs of urethral stricture.

Abstract

We present the case of a 55 year old patient under immunosuppressive treatment who developed multiple anogenital condylomata acuminata. Urethroscopy showed extensive condylomatous involvement of the entire penile urethra. Due to the potential morbidity of any surgical approach, we opted for an experimental treatment with Imiquimod (250 mg 5%-Imiquimod intraurethrally 3 times weekly), which was well tolerated. After a remarkable initial response and a continuous decline in the number of lesions, only minimal residual condylomata were left after 15 months. These were resected with the Holmium:YAG laser. Follow-up urethroscopy at three months showed no recurrence or signs of urethral stricture.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Urological Clinic
04 Faculty of Medicine > University Hospital Zurich > Dermatology Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:25 June 2010
Deposited On:29 Jul 2010 02:58
Last Modified:07 Dec 2017 03:02
Publisher:Wiley-Blackwell
ISSN:1464-4096
Additional Information:bjui.org exklusive
Official URL:http://www.bjui.org/ContentFullItem.aspx?id=510&SectionType=1

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