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GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene


Ciardo, D E; Burger, S; Payer, M; Lee, C; McCallum, N (2010). GeneXpert captures unstable methicillin-resistant Staphylococcus aureus prone to rapidly losing the mecA gene. Journal of Clinical Microbiology, 48(8):3030-3032.

Abstract

A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.

Abstract

A cefoxitin-susceptible Staphylococcus aureus strain was identified by the Cepheid GeneXpert as methicillin-resistant S. aureus (MRSA). This strain was highly unstable and rapidly lost SCCmec upon subculturing in vitro, indicating that unstable MRSA is best detected by gene amplification-based methods.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2010
Deposited On:21 Jan 2011 11:16
Last Modified:05 Apr 2016 14:27
Publisher:American Society for Microbiology
ISSN:0095-1137
Publisher DOI:https://doi.org/10.1128/JCM.02113-09
PubMed ID:20534797

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