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Allele distribution of six STR/miniSTR loci (CD4, FABP2, D12S391, D14S1434, D22S1045 and D10S1248) for forensic purposes in Southeastern Brazil


dos Santos, L L; de Assis, J B; Reis, A H D O; Scliar, M D O; Carvalho, M R S; Vaintraub, M T; Vaintraub, P (2011). Allele distribution of six STR/miniSTR loci (CD4, FABP2, D12S391, D14S1434, D22S1045 and D10S1248) for forensic purposes in Southeastern Brazil. Annals of Human Biology, 38(1):110-113.

Abstract

BACKGROUND: Allele frequencies for six STR/miniSTR loci were determined in a sample of unrelated individuals from Southeastern Brazil.

METHODS AND RESULTS: No significant deviations from Hardy-Weinberg equilibrium proportions were observed for the loci investigated (p-values ≥ 0.2320). Statistical parameters of forensic interest such as heterozygosity (H), power of discrimination (PD) and power of exclusion (PE) were estimated. Except for marker FABP2, all STR/miniSTRs tested showed observed heterozygosities over 0.66.Combined power of discrimination and power of exclusion were 0.9999993 and 0.9925, respectively.

CONCLUSIONS: Due to their ease of analysis and high informativity, these new STR multiplexes will be useful for extending current marker sets for forensic and paternity purposes.

Abstract

BACKGROUND: Allele frequencies for six STR/miniSTR loci were determined in a sample of unrelated individuals from Southeastern Brazil.

METHODS AND RESULTS: No significant deviations from Hardy-Weinberg equilibrium proportions were observed for the loci investigated (p-values ≥ 0.2320). Statistical parameters of forensic interest such as heterozygosity (H), power of discrimination (PD) and power of exclusion (PE) were estimated. Except for marker FABP2, all STR/miniSTRs tested showed observed heterozygosities over 0.66.Combined power of discrimination and power of exclusion were 0.9999993 and 0.9925, respectively.

CONCLUSIONS: Due to their ease of analysis and high informativity, these new STR multiplexes will be useful for extending current marker sets for forensic and paternity purposes.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Plant and Microbial Biology
07 Faculty of Science > Zurich-Basel Plant Science Center
Dewey Decimal Classification:580 Plants (Botany)
Language:English
Date:2011
Deposited On:17 Feb 2011 18:39
Last Modified:05 Apr 2016 14:41
Publisher:Taylor & Francis
ISSN:0301-4460
Publisher DOI:https://doi.org/10.3109/03014460.2010.491488
PubMed ID:20545471

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