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Antigen processing for MHC presentation by autophagy


Münz, C (2010). Antigen processing for MHC presentation by autophagy. F1000 Biology Reports, (2):61.

Abstract

Autophagy delivers cytoplasmic constituents for lysosomal degradation. This catabolic pathway can be used to deliver intracellular antigens for major histocompatibility complex (MHC) class II presentation. In addition, recent evidence suggests that it also facilitates the processing of extracellular antigens for both MHC class I and II presentation.

Abstract

Autophagy delivers cytoplasmic constituents for lysosomal degradation. This catabolic pathway can be used to deliver intracellular antigens for major histocompatibility complex (MHC) class II presentation. In addition, recent evidence suggests that it also facilitates the processing of extracellular antigens for both MHC class I and II presentation.

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Additional indexing

Item Type:Journal Article, not refereed, further contribution
Communities & Collections:04 Faculty of Medicine > Institute of Experimental Immunology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Language:English
Date:2010
Deposited On:02 Feb 2011 10:44
Last Modified:21 Nov 2017 15:13
Publisher:Biology Reports Ltd
ISSN:1757-594X
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.3410/B2-61
PubMed ID:21173848

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