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Mutational spectrum and therapy response of metastasized GIST in Central Switzerland - a population-based study


Rössle, M; Hirschmann, A; Diebold, J (2011). Mutational spectrum and therapy response of metastasized GIST in Central Switzerland - a population-based study. European Journal of Cancer, 47(9):1305-1311.

Abstract

Our data support previous observations, that PDGFRα mutations play no important role in metastasized GISTs. The influence of Imatinib and Sunitinib therapy in metastasized GISTs with wild type genotype and c-kit exon 9 mutations needs further investigation.

Abstract

Our data support previous observations, that PDGFRα mutations play no important role in metastasized GISTs. The influence of Imatinib and Sunitinib therapy in metastasized GISTs with wild type genotype and c-kit exon 9 mutations needs further investigation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:27 Jul 2011 09:01
Last Modified:05 Apr 2016 14:57
Publisher:Elsevier
ISSN:0959-8049
Publisher DOI:https://doi.org/10.1016/j.ejca.2011.01.012
PubMed ID:21334201

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