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Prognostic impact and therapeutic implications of sentinel lymph node micro-metastases in early-stage breast cancer patients


Viehl, C T; Langer, I; Guller, U; Zanetti-Dällenbach, R; Moch, H; Wight, E; Oertli, D; Zuber, M (2011). Prognostic impact and therapeutic implications of sentinel lymph node micro-metastases in early-stage breast cancer patients. Journal of Surgical Oncology, 103(6):531-533.

Abstract

The prognostic value of sentinel lymph node (SLN) micro-metastases and the question whether patients with SLN micro-metastases should undergo axillary lymph node dissection remain a matter of great debate. Based on the current literature and on our own data, we provide suggestive evidence that SLN micro-metastases in early stage breast cancer patients appear to have prognostic value and should impact the decision-making regarding adjuvant therapy, however, do not necessarily require further surgical treatment.

Abstract

The prognostic value of sentinel lymph node (SLN) micro-metastases and the question whether patients with SLN micro-metastases should undergo axillary lymph node dissection remain a matter of great debate. Based on the current literature and on our own data, we provide suggestive evidence that SLN micro-metastases in early stage breast cancer patients appear to have prognostic value and should impact the decision-making regarding adjuvant therapy, however, do not necessarily require further surgical treatment.

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10 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:03 Aug 2011 06:58
Last Modified:07 Dec 2017 08:43
Publisher:Wiley-Blackwell
ISSN:0022-4790
Publisher DOI:https://doi.org/10.1002/jso.21693
PubMed ID:21480245

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