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Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green


de Graaf, W; Häusler, S; Heger, M; van Ginhoven, T M; van Cappellen, G; Bennink, R J; Kullak-Ublick, G A; Hesselmann, R; van Gulik, T M; Stieger, B (2011). Transporters involved in the hepatic uptake of (99m)Tc-mebrofenin and indocyanine green. Journal of Hepatology, 54(4):738-745.

Abstract

The transporter specificity of (99m)Tc-mebrofenin and ICG partially overlaps as both compounds are transported by OATP1B3. (99m)Tc-mebrofenin is also taken up by OATP1B1, whereas ICG is additionally transported by NTCP.

Abstract

The transporter specificity of (99m)Tc-mebrofenin and ICG partially overlaps as both compounds are transported by OATP1B3. (99m)Tc-mebrofenin is also taken up by OATP1B1, whereas ICG is additionally transported by NTCP.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Clinical Pharmacology and Toxicology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:23 Aug 2011 14:18
Last Modified:21 Nov 2017 15:27
Publisher:Elsevier
ISSN:0168-8278
Publisher DOI:https://doi.org/10.1016/j.jhep.2010.07.047
PubMed ID:21163547

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