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Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization


Orgogozo, J M; Gilman, S; Dartigues, J F; Laurent, B; Puel, M; Kirby, L C; Jouanny, P; Dubois, B; Eisner, L; Flitman, S; Michel, B F; Boada, M; Frank, A; Hock, C (2003). Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology, 61(1):46-54.

Abstract

Postvaccination meningoencephalitis occurred without clear relation to serum anti-Abeta42 antibody titers. Potential mechanisms such as T-cell and microglial activation may be responsible and are under consideration to develop a safer anti-Abeta immunotherapy for AD.

Abstract

Postvaccination meningoencephalitis occurred without clear relation to serum anti-Abeta42 antibody titers. Potential mechanisms such as T-cell and microglial activation may be responsible and are under consideration to develop a safer anti-Abeta immunotherapy for AD.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute for Regenerative Medicine (IREM)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2003
Deposited On:02 Sep 2011 06:27
Last Modified:16 Aug 2016 10:15
Publisher:American Academy of Neurology
ISSN:0028-3878
Publisher DOI:https://doi.org/10.1212/01.WNL.0000073623.84147.A8
PubMed ID:12847155

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