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Genetics, transcriptomics, and proteomics of Alzheimer's disease


Papassotiropoulos, A; Fountoulakis, M; Dunckley, T; Stephan, D A; Reiman, E M (2006). Genetics, transcriptomics, and proteomics of Alzheimer's disease. Journal of Clinical Psychiatry, 67(4):652-670.

Abstract

The development of high-throughput genotyping methods and of elaborated statistical analyses will contribute to the identification of genetic risk profiles related to the development and course of this devastating disease. The integration of knowledge derived from genetic, transcriptomic, and proteomic studies will greatly advance our understanding of the causes of Alzheimer's disease, improve our capability of establishing an early diagnosis, help define disease subgroups, and ultimately help to pave the road toward improved and tailored treatments.

Abstract

The development of high-throughput genotyping methods and of elaborated statistical analyses will contribute to the identification of genetic risk profiles related to the development and course of this devastating disease. The integration of knowledge derived from genetic, transcriptomic, and proteomic studies will greatly advance our understanding of the causes of Alzheimer's disease, improve our capability of establishing an early diagnosis, help define disease subgroups, and ultimately help to pave the road toward improved and tailored treatments.

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60 citations in Web of Science®
66 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute for Regenerative Medicine (IREM)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2006
Deposited On:06 Sep 2011 07:17
Last Modified:16 Aug 2016 10:14
Publisher:Physicians Postgraduate Press
ISSN:0160-6689
Free access at:PubMed ID. An embargo period may apply.
PubMed ID:16669732

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