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Safety of injectable opioid maintenance treatment for heroin dependence


Stoermer, R; Drewe, J; Dursteler-Mac Farland, K M; Hock, C; Mueller-Spahn, F; Ladewig, D; Stohler, R; Mager, R (2003). Safety of injectable opioid maintenance treatment for heroin dependence. Biological Psychiatry, 54(8):854-861.

Abstract

Opioid doses commonly prescribed in IV opioid treatment induce marked respiratory and circulatory depression, as well as occasionally irregular paroxysmal EEG activity. Further studies are needed to optimize the clinical practice of IV opioid treatment to prevent serious complications. Moreover, the extent of the observed effects raises questions about the appropriateness of IV opioid treatment in the present form.

Abstract

Opioid doses commonly prescribed in IV opioid treatment induce marked respiratory and circulatory depression, as well as occasionally irregular paroxysmal EEG activity. Further studies are needed to optimize the clinical practice of IV opioid treatment to prevent serious complications. Moreover, the extent of the observed effects raises questions about the appropriateness of IV opioid treatment in the present form.

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19 citations in Web of Science®
23 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute for Regenerative Medicine (IREM)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2003
Deposited On:08 Sep 2011 09:19
Last Modified:07 Dec 2017 08:59
Publisher:Elsevier
ISSN:0006-3223
Publisher DOI:https://doi.org/10.1016/S0006-3223(03)00290-7
PubMed ID:14550686

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