Header

UZH-Logo

Maintenance Infos

A parametric relief signal in human ventrolateral prefrontal cortex


Fujiwara, J; Tobler, Philippe N; Taira, M; Iijima, T; Tsutsui, K I (2009). A parametric relief signal in human ventrolateral prefrontal cortex. NeuroImage, 44(3):1163-1170.

Abstract

People experience relief whenever outcomes are better than they would have been, had an alternative course of action been chosen. Here we investigated the neuronal basis of relief with functional resonance imaging in a choice task in which the outcome of the chosen option and that of the unchosen option were revealed sequentially. We found parametric activation increases in anterior ventrolateral prefrontal cortex with increasing relief (chosen outcomes better than unchosen outcomes). Conversely, anterior ventrolateral prefrontal activation was unrelated to the opposite of relief, increasing regret (chosen outcomes worse than unchosen outcomes). Furthermore, the anterior ventrolateral prefrontal activation was unrelated to primary gains and increased with relief irrespective of whether the chosen outcome was a loss or a gain. These results suggest that the anterior ventrolateral prefrontal cortex encodes a higher-order reward signal that lies at the core of current theories of emotion.

Abstract

People experience relief whenever outcomes are better than they would have been, had an alternative course of action been chosen. Here we investigated the neuronal basis of relief with functional resonance imaging in a choice task in which the outcome of the chosen option and that of the unchosen option were revealed sequentially. We found parametric activation increases in anterior ventrolateral prefrontal cortex with increasing relief (chosen outcomes better than unchosen outcomes). Conversely, anterior ventrolateral prefrontal activation was unrelated to the opposite of relief, increasing regret (chosen outcomes worse than unchosen outcomes). Furthermore, the anterior ventrolateral prefrontal activation was unrelated to primary gains and increased with relief irrespective of whether the chosen outcome was a loss or a gain. These results suggest that the anterior ventrolateral prefrontal cortex encodes a higher-order reward signal that lies at the core of current theories of emotion.

Statistics

Citations

21 citations in Web of Science®
23 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

1 download since deposited on 27 Oct 2011
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Economics
08 University Research Priority Programs > Foundations of Human Social Behavior: Altruism and Egoism
Dewey Decimal Classification:170 Ethics
330 Economics
Language:English
Date:2009
Deposited On:27 Oct 2011 14:05
Last Modified:05 Apr 2016 15:03
Publisher:Elsevier
ISSN:1053-8119
Publisher DOI:https://doi.org/10.1016/j.neuroimage.2008.09.050
PubMed ID:18992349

Download

Preview Icon on Download
Content: Published Version
Filetype: PDF - Registered users only
Size: 689kB
View at publisher