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Comment on "additive genetic breeding values correlate with the load of partially deleterious mutations"


Postma, E (2011). Comment on "additive genetic breeding values correlate with the load of partially deleterious mutations". Science, 333(6047):1221.

Abstract

Tomkins et al. (Reports, 14 May 2010, p. 892) reported a strong negative correlation between breeding values and mutational load in cow-pea weevils. Here, I show that this result can be attributed to a statistical artifact. By testing the observed correlation against an incorrect null hypothesis, they find a negative correlation where one does not exist.

Abstract

Tomkins et al. (Reports, 14 May 2010, p. 892) reported a strong negative correlation between breeding values and mutational load in cow-pea weevils. Here, I show that this result can be attributed to a statistical artifact. By testing the observed correlation against an incorrect null hypothesis, they find a negative correlation where one does not exist.

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2 citations in Web of Science®
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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Institute of Evolutionary Biology and Environmental Studies
Dewey Decimal Classification:570 Life sciences; biology
590 Animals (Zoology)
Language:English
Date:September 2011
Deposited On:18 Nov 2011 12:47
Last Modified:05 Apr 2016 15:06
Publisher:American Association for the Advancement of Science (AAAS)
ISSN:0036-8075
Additional Information:Comment on: Science. 2010 May 14;328(5980):892-894.
Publisher DOI:https://doi.org/10.1126/science.1200996
PubMed ID:21885758
Other Identification Number:ISI:000294406400025

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