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NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus


Audry, M; Ciancanelli, M; Yang, K; Cobat, A; Chang, H H; Sancho-Shimizu, V; Lorenzo, L; Niehues, T; Reichenbach, J; Li, X X; Israel, A; Abel, L; Casanova, J L; Zhang, S Y; Jouanguy, E; Puel, A (2011). NEMO is a key component of NF-κB- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus. Journal of Allergy and Clinical Immunology, 128(3):610-617.

Abstract

Herpes simplex encephalitis may occur in patients carrying NF-κB essential modulator mutations, due to the impairment of NF-κB- and interferon regulatory factor 3-dependent-TLR3-mediated antiviral IFN production.

Abstract

Herpes simplex encephalitis may occur in patients carrying NF-κB essential modulator mutations, due to the impairment of NF-κB- and interferon regulatory factor 3-dependent-TLR3-mediated antiviral IFN production.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:19 Dec 2011 12:18
Last Modified:07 Dec 2017 10:25
Publisher:Elsevier
ISSN:0091-6749
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.jaci.2011.04.059
PubMed ID:21722947

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