Header

UZH-Logo

Maintenance Infos

Future dentistry: cell therapy meets tooth and periodontal repair and regeneration


Caton, J; Bostanci, N; Remboutsika, E; De Bari, C; Mitsiadis, T A (2011). Future dentistry: cell therapy meets tooth and periodontal repair and regeneration. Journal of Cellular and Molecular Medicine, 15(5):1054-1065.

Abstract

Cell-based tissue repair of the tooth and - tooth-supporting - periodontal ligament (PDL) is a new attractive approach that complements traditional restorative or surgical techniques for replacement of injured or pathologically damaged tissues. In such therapeutic approaches, stem cells and/or progenitor cells are manipulated in vitro and administered to patients as living and dynamic biological agents. In this review, we discuss the clonogenic potential of human dental and periodontal tissues such as the dental pulp and the PDL and their potential for tooth and periodontal repair and/or regeneration. We propose novel therapeutic approaches using stem cells or progenitor cells, which are targeted to regenerate the lost dental or periodontal tissue.

Abstract

Cell-based tissue repair of the tooth and - tooth-supporting - periodontal ligament (PDL) is a new attractive approach that complements traditional restorative or surgical techniques for replacement of injured or pathologically damaged tissues. In such therapeutic approaches, stem cells and/or progenitor cells are manipulated in vitro and administered to patients as living and dynamic biological agents. In this review, we discuss the clonogenic potential of human dental and periodontal tissues such as the dental pulp and the PDL and their potential for tooth and periodontal repair and/or regeneration. We propose novel therapeutic approaches using stem cells or progenitor cells, which are targeted to regenerate the lost dental or periodontal tissue.

Statistics

Citations

32 citations in Web of Science®
36 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

2 downloads since deposited on 20 Dec 2011
0 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Institute of Oral Biology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:20 Dec 2011 14:06
Last Modified:05 Apr 2016 15:13
Publisher:Wiley-Blackwell
ISSN:1582-1838
Publisher DOI:https://doi.org/10.1111/j.1582-4934.2010.01251.x
PubMed ID:21199329

Download