Header

UZH-Logo

Maintenance Infos

Are there cervical spine findings at MR imaging that are specific to acute symptomatic whiplash injury? A prospective controlled study with four experienced blinded readers


Anderson, S E; Boesch, C; Zimmermann, H; Busato, A; Hodler, J; Bingisser, R; Ulbrich, E J; Nidecker, A; Buitrago-Téllez, C H; Bonel, H M; Heini, P; Schaeren, S; Sturzenegger, M (2012). Are there cervical spine findings at MR imaging that are specific to acute symptomatic whiplash injury? A prospective controlled study with four experienced blinded readers. Radiology, 262(2):567-575.

Abstract

Purpose: To compare the magnetic resonance (MR) imaging findings in patients with acute whiplash injury with those in matched control subjects.

Materials and Methods: In a prospective multicenter controlled study, from 2005 to 2008, 100 consecutive patients underwent 1.5-T MR imaging examinations of the cervical spine within 48 hours after a motor vehicle accident. Findings in these patients were compared in a blinded fashion with those in 100 age- and sex-matched healthy control subjects. Four blinded independent readers assessed the presence of occult vertebral body and facet fractures, vertebral body and facet contusions, intervertebral disk herniations, ligamentum nuchae strains, ligamentum nuchae tears, muscle strains or tears, and perimuscular fluid. Accuracy (as compared with clinical findings) and interobserver reliability were calculated.

Results: Accuracy of MR imaging and interreader reliability were generally poor (sensitivity, 0.328; specificity, 0.728; positive and negative likelihood ratios, 1.283 and 1.084, respectively). MR imaging findings significantly associated with whiplash injuries were occult fracture (P < .01), bone marrow contusion of the vertebral body (P = .01), muscle strain (P < .01) or tear (P < .01), and the presence of perimuscular fluid (P < .01). While 10 findings thought to be specific for whiplash trauma were significantly (P < .01) more frequent in patients (507 observations), they were also regularly found in healthy control subjects (237 observations). There were no serious occult injuries that required immediate therapy.

Conclusion: MR imaging at 1.5 T reveals only limited evidence of specific changes to the cervical spine and the surrounding tissues in patients with acute symptomatic whiplash injury compared with healthy control subjects.

Abstract

Purpose: To compare the magnetic resonance (MR) imaging findings in patients with acute whiplash injury with those in matched control subjects.

Materials and Methods: In a prospective multicenter controlled study, from 2005 to 2008, 100 consecutive patients underwent 1.5-T MR imaging examinations of the cervical spine within 48 hours after a motor vehicle accident. Findings in these patients were compared in a blinded fashion with those in 100 age- and sex-matched healthy control subjects. Four blinded independent readers assessed the presence of occult vertebral body and facet fractures, vertebral body and facet contusions, intervertebral disk herniations, ligamentum nuchae strains, ligamentum nuchae tears, muscle strains or tears, and perimuscular fluid. Accuracy (as compared with clinical findings) and interobserver reliability were calculated.

Results: Accuracy of MR imaging and interreader reliability were generally poor (sensitivity, 0.328; specificity, 0.728; positive and negative likelihood ratios, 1.283 and 1.084, respectively). MR imaging findings significantly associated with whiplash injuries were occult fracture (P < .01), bone marrow contusion of the vertebral body (P = .01), muscle strain (P < .01) or tear (P < .01), and the presence of perimuscular fluid (P < .01). While 10 findings thought to be specific for whiplash trauma were significantly (P < .01) more frequent in patients (507 observations), they were also regularly found in healthy control subjects (237 observations). There were no serious occult injuries that required immediate therapy.

Conclusion: MR imaging at 1.5 T reveals only limited evidence of specific changes to the cervical spine and the surrounding tissues in patients with acute symptomatic whiplash injury compared with healthy control subjects.

Statistics

Citations

16 citations in Web of Science®
26 citations in Scopus®
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Diagnostic and Interventional Radiology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:27 Dec 2011 09:44
Last Modified:05 Apr 2016 15:17
Publisher:Radiological Society of North America
ISSN:0033-8419
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1148/radiol.11102115
PubMed ID:22187629

Download

Full text not available from this repository.
View at publisher