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Deep brain stimulation in parkinsonian patients — ethical evaluation of cognitive, affective, and behavioral sequelae


Müller, S; Christen, M (2011). Deep brain stimulation in parkinsonian patients — ethical evaluation of cognitive, affective, and behavioral sequelae. AJOB Neuroscience, 2(1):3-13.

Abstract

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an important therapeutic advancement for the treatment of Parkinson's disease (PD). Its beneficial effects on motor functions are well established, but its cognitive, affective, and behavioral sequelae come increasingly into the focus of the medical and ethical discussion. In order to evaluate whether these side effects may counteract the beneficial effects of STN DBS on the patient's quality of life, we classify them along the dimensions “measurement complexity” and “weighted life-impact.” Based on this analysis, we discuss their ethical impact and propose guidelines for the clinical setting of STN DBS.

Abstract

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is an important therapeutic advancement for the treatment of Parkinson's disease (PD). Its beneficial effects on motor functions are well established, but its cognitive, affective, and behavioral sequelae come increasingly into the focus of the medical and ethical discussion. In order to evaluate whether these side effects may counteract the beneficial effects of STN DBS on the patient's quality of life, we classify them along the dimensions “measurement complexity” and “weighted life-impact.” Based on this analysis, we discuss their ethical impact and propose guidelines for the clinical setting of STN DBS.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Ethics and History of Medicine
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:13 Jan 2012 08:39
Last Modified:05 Apr 2016 15:23
Publisher:Taylor & Francis
ISSN:2150-7759
Publisher DOI:https://doi.org/10.1080/21507740.2010.533151
Official URL:http://www.tandfonline.com/doi/abs/10.1080/21507740.2010.533151

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