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Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland


Kenfak-Foguena, A; Schöni-Affolter, F; Bürgisser, P; Witteck, A; Darling, K E A; Kovari, H; Kaiser, L; Evison, J M; Elzi, L; Gurter-De La Fuente, V; Jost, J; Moradpour, D; Abravanel, F; Izpopet, J; Cavassini, M (2011). Hepatitis E Virus seroprevalence and chronic infections in patients with HIV, Switzerland. Emerging Infectious Diseases, 17(6):1074-8.

Abstract

We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation.

Abstract

We screened 735 HIV-infected patients in Switzerland with unexplained alanine aminotransferase elevation for hepatitis E virus (HEV) immunoglobulin G. Although HEV seroprevalence in this population is low (2.6%), HEV RNA can persist in patients with low CD4 cell counts. Findings suggest chronic HEV infection should be considered as a cause of persistent alanine aminotransferase elevation.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Infectious Diseases
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:21 Jan 2012 19:50
Last Modified:21 Nov 2017 15:46
Publisher:National Center for Infectious Diseases
ISSN:1080-6040
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.3201/eid1706.101067
Official URL:http://wwwnc.cdc.gov/eid/article/17/6/10-1067_article.htm
PubMed ID:21749774

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