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Anabolic steroids reduce muscle damage caused by rotator cuff tendon release in an experimental study in rabbits


Gerber, C; Meyer, D C; Nuss, Katja M; Farshad, Mazda (2011). Anabolic steroids reduce muscle damage caused by rotator cuff tendon release in an experimental study in rabbits. Journal of Bone and Joint Surgery. American Volume, 93(23):2189-2195.

Abstract

To our knowledge, this is the first documentation of partial prevention of important muscle alterations after retraction of the supraspinatus musculotendinous unit caused by tendon disruption. Nandrolone decanoate administration in the phase after tendon release prevented fatty infiltration of the supraspinatus muscle and reduced functional muscle impairment caused by myotendinous retraction in this rabbit rotator cuff model, but two of seven rabbits that received the drug developed infections.

Abstract

To our knowledge, this is the first documentation of partial prevention of important muscle alterations after retraction of the supraspinatus musculotendinous unit caused by tendon disruption. Nandrolone decanoate administration in the phase after tendon release prevented fatty infiltration of the supraspinatus muscle and reduced functional muscle impairment caused by myotendinous retraction in this rabbit rotator cuff model, but two of seven rabbits that received the drug developed infections.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Balgrist University Hospital, Swiss Spinal Cord Injury Center
05 Vetsuisse Faculty > Veterinary Clinic > Equine Department
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:24 Feb 2012 21:57
Last Modified:17 Feb 2018 15:29
Publisher:Boston, Journal of Bone and Joint Surgery
ISSN:0021-9355
OA Status:Green
Publisher DOI:https://doi.org/10.2106/JBJS.J.01589
PubMed ID:22159854

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