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Hepatocellular carcinoma: When to consider surgery?


Melloul, E; Lesurtel, M; Clavien, P A (2011). Hepatocellular carcinoma: When to consider surgery? In: Williams, R; Taylor-Robinson, S D. Clinical Dilemmas in Primary Liver Cancer. Oxford, GB: Blackwell-Wiley Publishing, 160-167.

Abstract

Hepatocellular carcinoma (HCC) is the most frequent primary hepatic tumour, and 90% of the cases occur in patients with chronic underlying liver disease. Liver transplantation and liver resection are the two curative treatment options. However, liver transplantation cannot be proposed in all patients with HCC due to donor scarcity and the limitations of transplant criteria in this context. Liver resection is as a result becoming the best alternative treatment, providing that liver function is not altered and the future liver remnant volume is adequate. This Chapter focuses on the indications for safe liver resection in HCC patients associated with normal liver parenchyma or with underlying chronic liver disease. The short and long-term outcomes after liver resection for HCC will also be reported.

Abstract

Hepatocellular carcinoma (HCC) is the most frequent primary hepatic tumour, and 90% of the cases occur in patients with chronic underlying liver disease. Liver transplantation and liver resection are the two curative treatment options. However, liver transplantation cannot be proposed in all patients with HCC due to donor scarcity and the limitations of transplant criteria in this context. Liver resection is as a result becoming the best alternative treatment, providing that liver function is not altered and the future liver remnant volume is adequate. This Chapter focuses on the indications for safe liver resection in HCC patients associated with normal liver parenchyma or with underlying chronic liver disease. The short and long-term outcomes after liver resection for HCC will also be reported.

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Item Type:Book Section, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Visceral and Transplantation Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2011
Deposited On:03 Mar 2012 15:52
Last Modified:17 Feb 2018 15:44
Publisher:Blackwell-Wiley Publishing
ISBN:978-0-470-65797-3
Additional Information:Online 2011 erschienen, Print 2012 erschienen.
OA Status:Closed
Publisher DOI:https://doi.org/10.1002/9781119962205.ch23

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