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Neue Biomarker für Prostatakarzinom


Provenzano, Maurizio (2012). Neue Biomarker für Prostatakarzinom. Praxis, 101(2):115-121.

Abstract

Prostate cancer (PCa) is one of the most common solid cancers and one of the most important causes of morbidity and mortality worldwide in men. So far, several efforts have been devoted to identify prostate cancer biomarkers, which allow a discrimination between indolent and clinically significant diseases, however with scarce results. The prostate-specific antigen (PSA) still remains the marker of choice for PCa diagnosis, prognosis, and «active surveillance». Thus, a sensitive and specific independent indicator, easy to screen in blood or urine is still not available. This review will provide a new insight into the role of previous (i.e. PSA) and new biomarkers, to use separately or in combination for prostate cancer screening and early detection programs.

Abstract

Prostate cancer (PCa) is one of the most common solid cancers and one of the most important causes of morbidity and mortality worldwide in men. So far, several efforts have been devoted to identify prostate cancer biomarkers, which allow a discrimination between indolent and clinically significant diseases, however with scarce results. The prostate-specific antigen (PSA) still remains the marker of choice for PCa diagnosis, prognosis, and «active surveillance». Thus, a sensitive and specific independent indicator, easy to screen in blood or urine is still not available. This review will provide a new insight into the role of previous (i.e. PSA) and new biomarkers, to use separately or in combination for prostate cancer screening and early detection programs.

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Additional indexing

Other titles:New biomarkers in prostate cancer
Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Urological Clinic
04 Faculty of Medicine > University Hospital Zurich > Division of Surgical Research
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2012
Deposited On:19 Jul 2012 14:37
Last Modified:30 May 2017 06:34
Publisher:Hans Huber
ISSN:1661-8157
Publisher DOI:https://doi.org/10.1024/1661-8157/a000819
PubMed ID:22252593

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