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The sigma B regulon influences internalization of Staphylococcus aureus by osteoblasts


Nair, Sean P; Bischoff, Markus; Senn, Maria M; Berger-Bächi, Brigitte (2003). The sigma B regulon influences internalization of Staphylococcus aureus by osteoblasts. Infection and Immunity, 71(7):4167-4170.

Abstract

Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does not necessarily account for the differences in the capacities of strains to be internalized.

Abstract

Individual strains of Staphylococcus aureus have different capacities to become internalized by osteoblasts. Here we report that the levels of sigma(B) expressed by S. aureus correlate with the capacity of this bacterium to be internalized by osteoblasts. However, sigma(B) is not essential for internalization and does not necessarily account for the differences in the capacities of strains to be internalized.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Medical Microbiology
Dewey Decimal Classification:570 Life sciences; biology
610 Medicine & health
Date:2003
Deposited On:20 Jul 2012 19:50
Last Modified:08 Aug 2017 10:34
Publisher:American Society for Microbiology
ISSN:0019-9567
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1128/IAI.71.7.4167–4170.2003
PubMed ID:12819110

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