Header

UZH-Logo

Maintenance Infos

Mnohocetné endokrinni neoplazie u psa - kazuistika


Kolevska, J; Vlach, D; Hrabeta, J; Novotny, L; Pospischil, Andreas (2012). Mnohocetné endokrinni neoplazie u psa - kazuistika. Veterinářství, 62(1):16-20.

Abstract

Multiple endocrine neoplasia (MEN) embodies a group of diseases in human patients and domestic animals that are characterized by neoplasia of two or more endocrine tissues. In humans, MEN is grouped into three major syndromes: MEN-1, MEN2A, and MEN-2B. MEN-1 is an autosomal dominant hereditary syndrome resulting from the mutation of the menin gne, which codes for a protein involved in transcription inhibition. The various mutations identified in the menin gene sequence of patients with MEN-1 have indicated correlation with development of different tumor phenotypes. MEN-like syndromes in dogs, cats, horses, bulls, and ferrets have been reported. The presented case report described a simultaneous occurrence of malignant insulinoma and thyroid adenocarcinoma in a seven-year-old, female Irish Setter with the episodes of weakness and collapses.

Abstract

Multiple endocrine neoplasia (MEN) embodies a group of diseases in human patients and domestic animals that are characterized by neoplasia of two or more endocrine tissues. In humans, MEN is grouped into three major syndromes: MEN-1, MEN2A, and MEN-2B. MEN-1 is an autosomal dominant hereditary syndrome resulting from the mutation of the menin gne, which codes for a protein involved in transcription inhibition. The various mutations identified in the menin gene sequence of patients with MEN-1 have indicated correlation with development of different tumor phenotypes. MEN-like syndromes in dogs, cats, horses, bulls, and ferrets have been reported. The presented case report described a simultaneous occurrence of malignant insulinoma and thyroid adenocarcinoma in a seven-year-old, female Irish Setter with the episodes of weakness and collapses.

Statistics

Downloads

186 downloads since deposited on 11 Sep 2012
15 downloads since 12 months
Detailed statistics

Additional indexing

Other titles:Multiple endocrine neoplasia in a dog
Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Pathology
Dewey Decimal Classification:570 Life sciences; biology
Language:Czech
Date:2012
Deposited On:11 Sep 2012 13:36
Last Modified:16 Feb 2018 23:48
Publisher:Statní zemědělské nakladatelství
ISSN:0506-8231
OA Status:Green
Related URLs:http://www.vetweb.cz/ (Publisher)

Download

Download PDF  'Mnohocetné endokrinni neoplazie u psa - kazuistika'.
Preview
Filetype: PDF
Size: 10MB