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How specific are the vaginal secretion mRNA-markers HBD1 and MUC4?


Cossu, C; Germann, U; Kratzer, A; Bär, W; Haas, C (2009). How specific are the vaginal secretion mRNA-markers HBD1 and MUC4? Forensic Science International: Genetics Supplement Series, 2(1):536-537.

Abstract

mRNA profiling is a new method for the identification of body fluids. We evaluated the specificity of the two supposedly vaginal secretion specific mRNA-markers HBD1 and MUC4 and the cross-reactivity with other mucous membranes. Both mRNA-markers reliably detect vaginal secretions from women of all ages (14–82 years), but they cross-react with other mucous membranes like buccal cells, or diverse mucous membranes taken from corpses.

Abstract

mRNA profiling is a new method for the identification of body fluids. We evaluated the specificity of the two supposedly vaginal secretion specific mRNA-markers HBD1 and MUC4 and the cross-reactivity with other mucous membranes. Both mRNA-markers reliably detect vaginal secretions from women of all ages (14–82 years), but they cross-react with other mucous membranes like buccal cells, or diverse mucous membranes taken from corpses.

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Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Legal Medicine
Dewey Decimal Classification:340 Law
610 Medicine & health
Language:English
Date:2009
Deposited On:16 Oct 2012 13:09
Last Modified:05 Apr 2016 15:59
Publisher:Elsevier
ISSN:1875-175X
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1016/j.fsigss.2009.08.063

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