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Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient


Tischler, Verena; Schuurmans, Macé M; Boehler, Annette; Gaspert, Ariana (2012). Crystal precipitation and granulomatous inflammation in multiple organs after foscarnet therapy in a lung transplant recipient. Journal of Heart and Lung Transplantation, 31(9):1037-1040.

Abstract

We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant cytomegalovirus (CMV) reactivation. This is the first description of systemic crystal precipitation and granulomatous inflammation associated with foscarnet therapy with predominant involvement of the heart, kidneys and lungs.

Abstract

We present the case of a lung transplant recipient with disseminated crystal precipitation, and granulomatous and fibrinous inflammation after therapy with foscarnet (Foscavir; AstraZeneca, Zug, Switzerland) for recurring ganciclovir-resistant cytomegalovirus (CMV) reactivation. This is the first description of systemic crystal precipitation and granulomatous inflammation associated with foscarnet therapy with predominant involvement of the heart, kidneys and lungs.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:18 Oct 2012 06:23
Last Modified:18 Feb 2018 07:33
Publisher:Elsevier
ISSN:1053-2498
OA Status:Closed
Publisher DOI:https://doi.org/10.1016/j.healun.2012.05.008
PubMed ID:22766024

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