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Primary Leiomyosarcoma in the Heart of a Guinea Pig


Vogler, B R; Vetsch, E; Wernick, M B; Sydler, T; Wiederkehr, D D (2012). Primary Leiomyosarcoma in the Heart of a Guinea Pig. Journal of Comparative Pathology, 147(4):452-454.

Abstract

Leiomyosarcoma was diagnosed in the heart of a 3-year-old female guinea pig. Neoplastic tissue was located in the ventricular septum extending into the right ventricular lumen, but was not obvious grossly. Microscopically, the mass was nodular and infiltrative and was composed of streams and bundles of spindle cells. Immunohistochemically, the neoplastic cells expressed vimentin and α-smooth muscle actin. There was no cross striation of the muscle cells. This is the first report of cardiac leiomyosarcoma in a guinea pig.

Abstract

Leiomyosarcoma was diagnosed in the heart of a 3-year-old female guinea pig. Neoplastic tissue was located in the ventricular septum extending into the right ventricular lumen, but was not obvious grossly. Microscopically, the mass was nodular and infiltrative and was composed of streams and bundles of spindle cells. Immunohistochemically, the neoplastic cells expressed vimentin and α-smooth muscle actin. There was no cross striation of the muscle cells. This is the first report of cardiac leiomyosarcoma in a guinea pig.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:05 Vetsuisse Faculty > Institute of Veterinary Pathology
05 Vetsuisse Faculty > Veterinary Clinic > Department of Small Animals
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:2012
Deposited On:09 Nov 2012 08:09
Last Modified:05 Apr 2016 16:03
Publisher:Elsevier
ISSN:0021-9975
Publisher DOI:https://doi.org/10.1016/j.jcpa.2012.04.005
PubMed ID:22770427

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