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Magnetic resonance imaging-based neuromorphometry in single patients – A proposal for its usefulness


Hänggi, Jürgen (2012). Magnetic resonance imaging-based neuromorphometry in single patients – A proposal for its usefulness. Zeitschrift für Neuropsychologie, 23(2):81-96.

Abstract

The usefulness of MRI-based neuromorphometry for the investigation of single patients is described. A longitudinal cortical thickness analysis in a patient revealed lateral temporal lobe atrophy, suggesting rather semantic than frontotemporal dementia. A boy
with the diagnosis of ADHD and control boys were compared and showed cortical thickness increases in the patient in the orbitofrontal cortex contradicting ADHD and suggesting disturbed social behaviour. The multiple synaesthetes E.S. was compared with control groups and showed hyperconnectivity between auditory and gustatory brain regions suggesting that interval-taste synaesthesia is rooted in anatomical alterations. McLeod syndrome patients were investigated and revealed severe atrophy of the caudate nucleus bilateral across time. Additionally, statistical recommendations for the comparison of MRI data of single patients are provided.

Abstract

The usefulness of MRI-based neuromorphometry for the investigation of single patients is described. A longitudinal cortical thickness analysis in a patient revealed lateral temporal lobe atrophy, suggesting rather semantic than frontotemporal dementia. A boy
with the diagnosis of ADHD and control boys were compared and showed cortical thickness increases in the patient in the orbitofrontal cortex contradicting ADHD and suggesting disturbed social behaviour. The multiple synaesthetes E.S. was compared with control groups and showed hyperconnectivity between auditory and gustatory brain regions suggesting that interval-taste synaesthesia is rooted in anatomical alterations. McLeod syndrome patients were investigated and revealed severe atrophy of the caudate nucleus bilateral across time. Additionally, statistical recommendations for the comparison of MRI data of single patients are provided.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:06 Faculty of Arts > Institute of Psychology
Dewey Decimal Classification:150 Psychology
Language:English
Date:2012
Deposited On:17 Dec 2012 08:53
Last Modified:07 Dec 2017 17:37
Publisher:Hans Huber
ISSN:1016-264X
Additional Information:Diese Artikelfassung entspricht nicht vollständig dem in der Zeitschrift veröffentlichten Artikel. Dies ist nicht die Originalversion des Artikels und kann daher nicht zur Zitierung herangezogen werden
Publisher DOI:https://doi.org/10.1024/1016-264X/a000065

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