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In vitro studies on odontogenic tumors


Catón, Javier; Mitsiadis, Thimios A; Morgan, Peter R (2012). In vitro studies on odontogenic tumors. Methods in Molecular Biology, 887:167-177.

Abstract

Ameloblastomas are uncommon benign neoplasms of the jaws. They originate from dental epithelial cells, but they are not capable of mineralizing or forming enamel. The study of these tumors is limited to live tissue collected from patients during scheduled surgery. Ameloblastomas grow slowly in vivo and this property is translated to their behavior in vitro. Here, we describe the methods to culture ameloblastomas in organotypic cultures, as well as to isolate stem/progenitor cells from these tumors.

Abstract

Ameloblastomas are uncommon benign neoplasms of the jaws. They originate from dental epithelial cells, but they are not capable of mineralizing or forming enamel. The study of these tumors is limited to live tissue collected from patients during scheduled surgery. Ameloblastomas grow slowly in vivo and this property is translated to their behavior in vitro. Here, we describe the methods to culture ameloblastomas in organotypic cultures, as well as to isolate stem/progenitor cells from these tumors.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Center for Dental Medicine > Institute of Oral Biology
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2012
Deposited On:21 Dec 2012 09:51
Last Modified:05 Apr 2016 16:13
Publisher:Humana Press
ISSN:1064-3745
Publisher DOI:https://doi.org/10.1007/978-1-61779-860-3_15
PubMed ID:22566055

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