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Towards virtual know ledge broker services for semantic integration of life science literature and data sources


Harrow, Ian; Filsell, Wendy; Woollard, Peter; Dix, Ian; Braxtenthaler, Michael; Gedye, Richard; Hoole, David; Kidd, Richard; Wilson, Jabe; Rebholz-Schuhmann, Dietrich (2013). Towards virtual know ledge broker services for semantic integration of life science literature and data sources. Drug Discovery Today, 18(9-10):428-434.

Abstract

Research in the life sciences requires ready access to primary data, derived information and relevant knowledge from a multitude of sources. Integration and interoperability of such resources are critical for sharing content across research domains relevant to the life sciences. In this article we present a perspective review of data integration with emphasis on a semantics driven approach to data integration that pushes content into a shared infrastructure, reduces data redundancy and clarifies any inconsistencies. This enables much improved access to life science data from numerous primary sources. The Semantic Enrichment of the Scientific Literature (SESL) pilot project demonstrates feasibility for using already available open semantic web standards and technologies to integrate public and proprietary data resources, which span structured and unstructured content. This has been accomplished through a precompetitive consortium, which provides a cost effective approach for numerous stakeholders to work together to solve common problems.

Abstract

Research in the life sciences requires ready access to primary data, derived information and relevant knowledge from a multitude of sources. Integration and interoperability of such resources are critical for sharing content across research domains relevant to the life sciences. In this article we present a perspective review of data integration with emphasis on a semantics driven approach to data integration that pushes content into a shared infrastructure, reduces data redundancy and clarifies any inconsistencies. This enables much improved access to life science data from numerous primary sources. The Semantic Enrichment of the Scientific Literature (SESL) pilot project demonstrates feasibility for using already available open semantic web standards and technologies to integrate public and proprietary data resources, which span structured and unstructured content. This has been accomplished through a precompetitive consortium, which provides a cost effective approach for numerous stakeholders to work together to solve common problems.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Informatics
Dewey Decimal Classification:000 Computer science, knowledge & systems
Uncontrolled Keywords:Semantic Web, data integration, text mining, interoperability, bioinformatics, Diabetes mellitues
Language:English
Date:2013
Deposited On:20 Dec 2012 07:50
Last Modified:07 Dec 2017 17:44
Publisher:Elsevier
ISSN:1359-6446
Funders:Pistoia Alliance
Publisher DOI:https://doi.org/10.1016/j.drudis.2012.11.012

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