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Orale Metastase eines Nierenzellkarzinoms Ein Fallbericht über die Erstmanifestation eines Nierenzellkarzinoms als ossäre Metastase im Unterkiefer


Wittig, Jörn; Bredell, Marius Gustav; Kruse, Astrid; Haralambieva, Eugenia; Grätz, Klaus Wilhelm; Lübbers, Heinz-Theo (2012). Orale Metastase eines Nierenzellkarzinoms Ein Fallbericht über die Erstmanifestation eines Nierenzellkarzinoms als ossäre Metastase im Unterkiefer. Schweizer Monatsschrift für Zahnmedizin, 122(7-8):619-627.

Abstract

Tumorous lesions of the oral cavity are mostly of dental or local pathological origin. On occasion, they may have a distant origin outside the field of dentistry. Under certain circumstances, this can lead to serious consequences. Renal cell carcinomas are known for their frequent metastasis to the lungs, liver, bones, and brain. Metastases to the oral cavity are rare. Case report: A 68-year-old woman with previously unknown renal cell carcinoma is presented. By biopsy of a suspicious lesion, an intraoral clear cell carcinoma was diagnosed. In the following tumor staging, a metastasizing clear cell renal cell carcinoma was identified as the focus and a systemic therapy was initiated. Summary: This case report exemplarily shows the importance of timely histological verification of each new intraoral lesion. Under certain circumstances, a diagnosis of a surprising and potentially life-threatening condition may be made in time to initiate adequate treatment.

Abstract

Tumorous lesions of the oral cavity are mostly of dental or local pathological origin. On occasion, they may have a distant origin outside the field of dentistry. Under certain circumstances, this can lead to serious consequences. Renal cell carcinomas are known for their frequent metastasis to the lungs, liver, bones, and brain. Metastases to the oral cavity are rare. Case report: A 68-year-old woman with previously unknown renal cell carcinoma is presented. By biopsy of a suspicious lesion, an intraoral clear cell carcinoma was diagnosed. In the following tumor staging, a metastasizing clear cell renal cell carcinoma was identified as the focus and a systemic therapy was initiated. Summary: This case report exemplarily shows the importance of timely histological verification of each new intraoral lesion. Under certain circumstances, a diagnosis of a surprising and potentially life-threatening condition may be made in time to initiate adequate treatment.

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Additional indexing

Other titles:Oral metastasis of a renal cell carcinoma. A case report concerning the first manifestation of a renal cell carcinoma as bone metastasis in the mandible
Item Type:Journal Article, refereed, further contribution
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Division of Surgical Research
04 Faculty of Medicine > University Hospital Zurich > Institute of Pathology and Molecular Pathology
04 Faculty of Medicine > Center for Dental Medicine > Clinic for Cranio-Maxillofacial Surgery
Dewey Decimal Classification:610 Medicine & health
Language:German
Date:2012
Deposited On:29 Dec 2012 14:54
Last Modified:05 Apr 2016 16:15
Publisher:Schweizerische Zahnärzte-Gesellschaft SSO
ISSN:0256-2855
PubMed ID:22915025

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