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Similarity of chemotherapy histories based on imputed values


Khayati, Mourad; Anderson, Jay Martin; Böhlen, Michael Hanspeter; Gamper, Johann; Mitterer, Manfred (2012). Similarity of chemotherapy histories based on imputed values. International Journal of Medical Engineering and Informatics, 4(3):282-298.

Abstract

The comparison of time series of multivariate data is a long-standing problem in many applications in the clinical domain. We propose two approaches to retrieve from a hospital data warehouse the k patients P1, ..., Pn with a chemotherapy history that is most similar to patient Q: the first is based on warping distance, together with an initial alignment using imputed values. The second is based on the volume of the Kiviat tube. In implementing the Euclidean distance, we investigate the addition of null events to achieve similar cardinality, and dynamic time warping, a widely-used technique in the comparison of time series data. The investigations are based on a real world clinical database.

Abstract

The comparison of time series of multivariate data is a long-standing problem in many applications in the clinical domain. We propose two approaches to retrieve from a hospital data warehouse the k patients P1, ..., Pn with a chemotherapy history that is most similar to patient Q: the first is based on warping distance, together with an initial alignment using imputed values. The second is based on the volume of the Kiviat tube. In implementing the Euclidean distance, we investigate the addition of null events to achieve similar cardinality, and dynamic time warping, a widely-used technique in the comparison of time series data. The investigations are based on a real world clinical database.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Informatics
Dewey Decimal Classification:000 Computer science, knowledge & systems
Language:English
Date:2012
Deposited On:14 Jan 2013 16:29
Last Modified:05 Apr 2016 16:16
Publisher:Inderscience Publishers
ISSN:1755-0653
Publisher DOI:https://doi.org/10.1504/IJMEI.2012.048389
Other Identification Number:merlin-id:7763

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