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Electrocardiogram-triggered, higher order, projection-based B(0) shimming allows for fast and reproducible shim convergence in spinal cord (1) H MRS - Zurich Open Repository and Archive


Hock, Andreas; Fuchs, Alexander; Boesiger, Peter; Kollias, Spyros S; Henning, Anke (2013). Electrocardiogram-triggered, higher order, projection-based B(0) shimming allows for fast and reproducible shim convergence in spinal cord (1) H MRS. NMR in biomedicine, 26(3):329-335.

Abstract

(1) H MRS allows insight into the chemical composition of the central nervous system. However, as a result of technical challenges, it has rarely been applied to the spinal cord. In particular, the strong susceptibility changes around the spinal cord and the pulsatile flow of the cerebrospinal fluid lead to distinct B(0) field distortions which often considerably degrade the spectral quality. Hence, B(0) shimming is one of the main challenges in (1) H MRS of the spinal cord. Electrocardiogram (ECG)-triggered, higher order, projection-based B(0) shimming was introduced and compared with both conventional projection-based B(0) shimming and B(0) shimming based on ECG-triggered, three-dimensional B(0) field mapping. The linewidth of the unsuppressed water peak was used to evaluate the reproducibility and the potential improvement to B(0) homogeneity. The use of ECG-triggered projection-based B(0) shimming in combination with ECG triggering during preparation phases and triggering during acquisition of the spectra is the most robust method and thus helps to improve the spectral quality for MRS of the spinal cord.

Abstract

(1) H MRS allows insight into the chemical composition of the central nervous system. However, as a result of technical challenges, it has rarely been applied to the spinal cord. In particular, the strong susceptibility changes around the spinal cord and the pulsatile flow of the cerebrospinal fluid lead to distinct B(0) field distortions which often considerably degrade the spectral quality. Hence, B(0) shimming is one of the main challenges in (1) H MRS of the spinal cord. Electrocardiogram (ECG)-triggered, higher order, projection-based B(0) shimming was introduced and compared with both conventional projection-based B(0) shimming and B(0) shimming based on ECG-triggered, three-dimensional B(0) field mapping. The linewidth of the unsuppressed water peak was used to evaluate the reproducibility and the potential improvement to B(0) homogeneity. The use of ECG-triggered projection-based B(0) shimming in combination with ECG triggering during preparation phases and triggering during acquisition of the spectra is the most robust method and thus helps to improve the spectral quality for MRS of the spinal cord.

Citations

13 citations in Web of Science®
14 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neuroradiology
04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Language:English
Date:2013
Deposited On:29 Jan 2013 08:33
Last Modified:05 Apr 2016 16:20
Publisher:Wiley-Blackwell
ISSN:0952-3480
Publisher DOI:https://doi.org/10.1002/nbm.2852
PubMed ID:23065738

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