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Bioinspired, releasable quorum sensing modulators


Gomes, José; Grunau, Alexander; Lawrence, Adrien K; Eberl, Leo; Gademann, Karl (2013). Bioinspired, releasable quorum sensing modulators. Chemical Communications, 49(2):155-157.

Abstract

We demonstrate the synthesis and immobilization of natural product hybrids featuring an acyl-homoserine lactone and a nitrodopamine onto biocompatible TiO(2) surfaces through an operationally simple dip-and-rinse procedure. The resulting immobilized hybrids were shown to be powerful quorum sensing (QS) activators in Pseudomonas strains acting by slow release from the surface.

Abstract

We demonstrate the synthesis and immobilization of natural product hybrids featuring an acyl-homoserine lactone and a nitrodopamine onto biocompatible TiO(2) surfaces through an operationally simple dip-and-rinse procedure. The resulting immobilized hybrids were shown to be powerful quorum sensing (QS) activators in Pseudomonas strains acting by slow release from the surface.

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20 citations in Web of Science®
20 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:07 Faculty of Science > Department of Plant and Microbial Biology
Dewey Decimal Classification:580 Plants (Botany)
Language:English
Date:2013
Deposited On:21 Mar 2013 16:00
Last Modified:07 Dec 2017 18:30
Publisher:Royal Society of Chemistry (RSC)
ISSN:1359-7345
Publisher DOI:https://doi.org/10.1039/c2cc37287h
PubMed ID:23169441

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