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Highly undersampled phase-contrast flow measurements using compartment-basedk-tprincipal component analysis


Giese, Daniel; Schaeffter, Tobias; Kozerke, Sebastian (2012). Highly undersampled phase-contrast flow measurements using compartment-basedk-tprincipal component analysis. Magnetic Resonance in Medicine, 69(2):434-443.

Abstract

The applicability of cine blood flow measurements in a clinical setting is often compromised by the long scan times associated with phase-contrast imaging. In this work, we propose an extension to the k-t principal component analysis method and demonstrate that by definition of spatial compartment-dependent temporal basis functions, significant improvements in reconstruction accuracy can be achieved relative to the original k-t principal component analysis and k-t SENSE formulations. Using this method, it is shown that prospective nominal undersampling of up to 16 corresponding to a net acceleration factor of 8 including training data acquisition can be realized while keeping the error in stroke volume below 5%. As a practical application, the acquisition of cine flow data in the aorta is demonstrated permitting assessment of two-dimensional velocity images and pulse wave velocities at 100 frames per second in a single breathhold per slice.

Abstract

The applicability of cine blood flow measurements in a clinical setting is often compromised by the long scan times associated with phase-contrast imaging. In this work, we propose an extension to the k-t principal component analysis method and demonstrate that by definition of spatial compartment-dependent temporal basis functions, significant improvements in reconstruction accuracy can be achieved relative to the original k-t principal component analysis and k-t SENSE formulations. Using this method, it is shown that prospective nominal undersampling of up to 16 corresponding to a net acceleration factor of 8 including training data acquisition can be realized while keeping the error in stroke volume below 5%. As a practical application, the acquisition of cine flow data in the aorta is demonstrated permitting assessment of two-dimensional velocity images and pulse wave velocities at 100 frames per second in a single breathhold per slice.

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17 citations in Web of Science®
19 citations in Scopus®
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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Institute of Biomedical Engineering
Dewey Decimal Classification:170 Ethics
610 Medicine & health
Language:English
Date:2012
Deposited On:14 Feb 2013 09:42
Last Modified:05 Apr 2016 16:26
Publisher:Wiley-Blackwell
ISSN:0740-3194
Publisher DOI:https://doi.org/10.1002/mrm.24273
PubMed ID:22528878

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