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Cannabis und Schizophrenie: neue Erkenntnisse in einer alten Debatte


Kawohl, W; Rössler, W (2008). Cannabis und Schizophrenie: neue Erkenntnisse in einer alten Debatte. Neuropsychiatrie, 22(4):223-229.

Abstract

The issue, whether the use of cannabis contains a higher risk to develop psychotic disorders, is disputed since the 1930s. Two questions are of central concern: Firstly, if the use of cannabis is causal for the development of psychotic disorders, and secondly, what the neurobiological connection consists of. In this review we give an overview on epidemiological studies concerning the issue and on neurobiological studies on the effects of cannabis in the brain. On the basis of cohort studies that have been conducted within the last decades and recent meta-analyses the hypothesized connection between cannabis use und psychotic disorders can be corroborated. The risk to develop psychotic symptoms and also schizophrenic psychoses is thus explicitly elevated for young people who use cannabis. Cannabis use can be considered a component cause, a dose dependency exists. An information of the public concerning this matter is required in order to prevent a rising incidence of psychotic disorders in times of an increasing ease of handling of cannabis.

Abstract

The issue, whether the use of cannabis contains a higher risk to develop psychotic disorders, is disputed since the 1930s. Two questions are of central concern: Firstly, if the use of cannabis is causal for the development of psychotic disorders, and secondly, what the neurobiological connection consists of. In this review we give an overview on epidemiological studies concerning the issue and on neurobiological studies on the effects of cannabis in the brain. On the basis of cohort studies that have been conducted within the last decades and recent meta-analyses the hypothesized connection between cannabis use und psychotic disorders can be corroborated. The risk to develop psychotic symptoms and also schizophrenic psychoses is thus explicitly elevated for young people who use cannabis. Cannabis use can be considered a component cause, a dose dependency exists. An information of the public concerning this matter is required in order to prevent a rising incidence of psychotic disorders in times of an increasing ease of handling of cannabis.

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Additional indexing

Other titles:Cannabis and Schizophrenia: new findings in an old debate
Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > Psychiatric University Hospital Zurich > Clinic for Clinical and Social Psychiatry Zurich West (former)
Dewey Decimal Classification:610 Medicine & health
Uncontrolled Keywords:Cannabis; Kausalität; Psychose; Schizophrenie; Tetrahydrocannabinol / cannabis; causality; psychosis; schizophrenia; tetrahydrocannabinol
Language:German
Date:2008
Deposited On:30 Dec 2008 10:06
Last Modified:05 Apr 2016 12:40
Publisher:Dustri
ISSN:0948-6259
Related URLs:http://www.dustri.de/ (Publisher)
PubMed ID:19080993

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