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On the future of mass-spectrometry-based lipidomics


Loizides-Mangold, Ursula (2013). On the future of mass-spectrometry-based lipidomics. FEBS Journal, 280:2817-2829.

Abstract

Lipids have highly diverse functions that go beyond cellular membrane structure and energy storage. One of the great challenges in lipid researchwill be to understand how the enormous complexity of lipid homeostasis is maintained. Genetic approaches combined with mass spectrometry-based lipidomics will help to elucidate how cells create and maintain their nonrandom lipid distribution within tissues, cells, organelles and lipid bilayers. Lipid homeostasis is crucial for many cellular processes and we are currently only beginning to understand the specific functions of lipids and the local environment that they create.

Abstract

Lipids have highly diverse functions that go beyond cellular membrane structure and energy storage. One of the great challenges in lipid researchwill be to understand how the enormous complexity of lipid homeostasis is maintained. Genetic approaches combined with mass spectrometry-based lipidomics will help to elucidate how cells create and maintain their nonrandom lipid distribution within tissues, cells, organelles and lipid bilayers. Lipid homeostasis is crucial for many cellular processes and we are currently only beginning to understand the specific functions of lipids and the local environment that they create.

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Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:Special Collections > SystemsX.ch
Special Collections > SystemsX.ch > Research, Technology and Development Projects > LipidX
Dewey Decimal Classification:570 Life sciences; biology
Language:English
Date:June 2013
Deposited On:22 Jun 2013 16:11
Last Modified:16 Feb 2018 17:49
Publisher:Wiley-Blackwell
ISSN:1742-464X
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1111/febs.12202

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