In 2009 Suprelorin® was released in Switzerland for the temporary suppression of fertility in male dogs. However, in practice it has also been used for the treatment of other conditions in male dogs as well as in bitches. These include the management of benign hyperplasia of the prostate, induction or suppression of oestrus and the treatment of side effects of gonadectomy. In feline reproductive medicine GnRH-agonists are also gaining importance. These various applications are listed in terms of treatment success and possible side effects after administration about which owners must be fully informed.