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Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele


Meuli, Martin; Meuli-Simmen, Claudia; Flake, Alan W; Zimmermann, Roland; Ochsenbein, Nicole; Scheer, Ianina; Mazzone, Luca; Moehrlen, Ueli (2013). Premiere use of Integra™ artificial skin to close an extensive fetal skin defect during open in utero repair of myelomeningocele. Pediatric Surgery International, 29(12):1321-1326.

Abstract

BACKGROUND: There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin.

MATERIAL AND METHODS: We use Integra™ artifical skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnataly to reinforce the repair site.

CONCLUSION: Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero.

Abstract

BACKGROUND: There are fetuses demonstrating very large myelomeningocele lesion which can not be covered with autochothonous skin.

MATERIAL AND METHODS: We use Integra™ artifical skin for intrauterine coverage of the back lesion. A reverse latissimus dorsi flap was used postnataly to reinforce the repair site.

CONCLUSION: Integra™ appears to be a suitable coverage for large soft tissue defects in utero. Moreover, a postnatal reverse latissimus dorsi flap appears to markedly strengthen tissue coverage over a spinal cord rescued in utero.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Obstetrics
04 Faculty of Medicine > University Children's Hospital Zurich > Medical Clinic
04 Faculty of Medicine > University Children's Hospital Zurich > Clinic for Surgery
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:2013
Deposited On:07 Oct 2013 13:19
Last Modified:16 Feb 2018 18:06
Publisher:Springer
ISSN:0179-0358
OA Status:Closed
Publisher DOI:https://doi.org/10.1007/s00383-013-3412-7
PubMed ID:24057923

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