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Hepatitis B vaccination campaign in a low endemicity area


Grob, P J; Rickenbach, M; Steffen, Robert; Wagner, Susanne; Kistler, G; Schmid, M; Gutzwiller, Felix (1985). Hepatitis B vaccination campaign in a low endemicity area. European Journal of Clinical Microbiology, 4(4):408-411.

Abstract

Between January 1982 and December 1983 14,666 high-risk individuals in the Canton of Zurich, which has one million inhabitants, received 36,234 hepatitis B vaccine injections. The annual number of acute hepatitis B cases dropped from an estimated 220 to 280 in 1981 to 177 in 1982 and 133 in 1983. This drop of 40-50% resulted mainly from reduced numbers of cases among health care workers, drug addicts and homosexuals. Vaccination was a factor responsible for the reduced incidence of hepatitis B among health care workers and drug addicts, high-risk categories substantial proportions of which had been vaccinated. There was no evidence of a secondary protective effect of vaccination extending to other high-risk groups.

Abstract

Between January 1982 and December 1983 14,666 high-risk individuals in the Canton of Zurich, which has one million inhabitants, received 36,234 hepatitis B vaccine injections. The annual number of acute hepatitis B cases dropped from an estimated 220 to 280 in 1981 to 177 in 1982 and 133 in 1983. This drop of 40-50% resulted mainly from reduced numbers of cases among health care workers, drug addicts and homosexuals. Vaccination was a factor responsible for the reduced incidence of hepatitis B among health care workers and drug addicts, high-risk categories substantial proportions of which had been vaccinated. There was no evidence of a secondary protective effect of vaccination extending to other high-risk groups.

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Additional indexing

Item Type:Journal Article, not refereed, original work
Communities & Collections:04 Faculty of Medicine > Epidemiology, Biostatistics and Prevention Institute (EBPI)
Dewey Decimal Classification:610 Medicine & health
Language:English
Date:1985
Deposited On:09 Oct 2013 14:35
Last Modified:07 Dec 2017 22:46
Publisher:Vieweg
ISSN:0722-2211
Publisher DOI:https://doi.org/10.1007/BF02148694
PubMed ID:4043059

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