Header

UZH-Logo

Maintenance Infos

Altered cortical activation from the hand after facial botulinum toxin treatment


Haenzi, Sara; Stefanics, Gabor; Lanaras, Tatjana; Calcagni, Maurizio; Ghosh, Arko (2014). Altered cortical activation from the hand after facial botulinum toxin treatment. Annals of Clinical and Translational Neurology, 1(1):64-68.

Abstract

Plastic interactions between face and hand cortical tactile circuits occur after severe injuries that affect the hand such as in amputation or spinal cord injury. However, whether loss of facial movements alters the cortical circuits involved in processing tactile inputs from the hand remains unknown. In this prospective observational study we used electroencephalography (EEG) to measure cortical activity evoked by tactile stimulation of the hands before and after botulinum toxin-A-induced facial paralysis. We found a reduction in the tactile event-related potentials (ERPs) 6 weeks after the treatment. This suggests that the limited paralysis of facial muscles induced during cosmetic interventions designed to smooth lines and wrinkles on the face is sufficient to alter the cortical processing of tactile inputs from the hand.

Abstract

Plastic interactions between face and hand cortical tactile circuits occur after severe injuries that affect the hand such as in amputation or spinal cord injury. However, whether loss of facial movements alters the cortical circuits involved in processing tactile inputs from the hand remains unknown. In this prospective observational study we used electroencephalography (EEG) to measure cortical activity evoked by tactile stimulation of the hands before and after botulinum toxin-A-induced facial paralysis. We found a reduction in the tactile event-related potentials (ERPs) 6 weeks after the treatment. This suggests that the limited paralysis of facial muscles induced during cosmetic interventions designed to smooth lines and wrinkles on the face is sufficient to alter the cortical processing of tactile inputs from the hand.

Statistics

Citations

2 citations in Web of Science®
5 citations in Scopus®
Google Scholar™

Altmetrics

Downloads

3 downloads since deposited on 03 Feb 2014
3 downloads since 12 months
Detailed statistics

Additional indexing

Item Type:Journal Article, refereed, further contribution
Communities & Collections:07 Faculty of Science > Institute of Neuroinformatics
04 Faculty of Medicine > Institute of Biomedical Engineering
04 Faculty of Medicine > University Hospital Zurich > Clinic for Reconstructive Surgery
Dewey Decimal Classification:570 Life sciences; biology
170 Ethics
610 Medicine & health
Language:English
Date:2014
Deposited On:03 Feb 2014 11:17
Last Modified:06 Sep 2017 20:54
Publisher:Wiley Open Access
ISSN:2328-9503
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1002/acn3.21
PubMed ID:25356383

Download

Preview Icon on Download
Preview
Content: Published Version
Filetype: PDF
Size: 248kB
View at publisher
Licence: Creative Commons: Attribution-NonCommercial-NoDerivs 3.0 Unported (CC BY-NC-ND 3.0)