Header

UZH-Logo

Maintenance Infos

Adaptive coding of reward value by dopamine neurons


Tobler, Philippe N; Fiorillo, Christopher D; Schultz, Wolfram (2005). Adaptive coding of reward value by dopamine neurons. Science, 307(5715):1642-1645.

Abstract

It is important for animals to estimate the value of rewards as accurately as possible. Because the number of potential reward values is very large, it is necessary that the brain's limited resources be allocated so as to discriminate better among more likely reward outcomes at the expense of less likely outcomes. We found that midbrain dopamine neurons rapidly adapted to the information provided by reward-predicting stimuli. Responses shifted relative to the expected reward value, and the gain adjusted to the variance of reward value. In this way, dopamine neurons maintained their reward sensitivity over a large range of reward values.

Abstract

It is important for animals to estimate the value of rewards as accurately as possible. Because the number of potential reward values is very large, it is necessary that the brain's limited resources be allocated so as to discriminate better among more likely reward outcomes at the expense of less likely outcomes. We found that midbrain dopamine neurons rapidly adapted to the information provided by reward-predicting stimuli. Responses shifted relative to the expected reward value, and the gain adjusted to the variance of reward value. In this way, dopamine neurons maintained their reward sensitivity over a large range of reward values.

Statistics

Citations

Dimensions.ai Metrics
628 citations in Web of Science®
660 citations in Scopus®
1036 citations in Microsoft Academic
Google Scholar™

Altmetrics

Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:03 Faculty of Economics > Department of Economics
Dewey Decimal Classification:330 Economics
Language:English
Date:2005
Deposited On:12 Dec 2013 09:56
Last Modified:19 Feb 2018 20:11
Publisher:American Association for the Advancement of Science
ISSN:0036-8075
OA Status:Closed
Free access at:Publisher DOI. An embargo period may apply.
Publisher DOI:https://doi.org/10.1126/science.1105370
PubMed ID:15761155

Download

Full text not available from this repository.
View at publisher

Get full-text in a library