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Calibration of a prototype NIRS oximeter against two commercial devices on a blood-lipid phantom


Hyttel-Sorensen, Simon; Kleiser, Stefan; Wolf, Martin; Greisen, Gorm (2013). Calibration of a prototype NIRS oximeter against two commercial devices on a blood-lipid phantom. Biomedical Optics Express, 4(9):1662-1672.

Abstract

In a blood-lipid liquid phantom the prototype near-infrared spectroscopy oximeter OxyPrem was calibrated against the INVOS® 5100c adult sensor in respect to values of regional tissue oxygen haemoglobin saturation (rStO2) for possible inclusion in the randomised clinical trial - SafeBoosC. In addition different commercial NIRS oximeters were compared on changing haemoglobin oxygen saturation and compared against co-oximetry. The best calibration was achieved with a simple offset and a linear scaling of the OxyPrem rStO2 values. The INVOS adult and pediatric sensor gave systematically different values, while the difference between the NIRO® 300 and the two INVOS sensors were magnitude dependent. The co-oximetry proved unreliable on such low haemoglobin and high Intralipid levels.

Abstract

In a blood-lipid liquid phantom the prototype near-infrared spectroscopy oximeter OxyPrem was calibrated against the INVOS® 5100c adult sensor in respect to values of regional tissue oxygen haemoglobin saturation (rStO2) for possible inclusion in the randomised clinical trial - SafeBoosC. In addition different commercial NIRS oximeters were compared on changing haemoglobin oxygen saturation and compared against co-oximetry. The best calibration was achieved with a simple offset and a linear scaling of the OxyPrem rStO2 values. The INVOS adult and pediatric sensor gave systematically different values, while the difference between the NIRO® 300 and the two INVOS sensors were magnitude dependent. The co-oximetry proved unreliable on such low haemoglobin and high Intralipid levels.

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Additional indexing

Item Type:Journal Article, refereed, original work
Communities & Collections:04 Faculty of Medicine > University Hospital Zurich > Clinic for Neonatology
Dewey Decimal Classification:610 Medicine & health
Date:2013
Deposited On:04 Feb 2014 07:58
Last Modified:07 Dec 2017 08:30
Publisher:Optical Society of America
ISSN:2156-7085
Free access at:PubMed ID. An embargo period may apply.
Publisher DOI:https://doi.org/10.1364/BOE.4.001662
Official URL:http://europepmc.org/abstract/MED/24049687
PubMed ID:24049687

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